Our children with PSC present unique challenges and are rarer than adults with PSC. We are privileged to hear from Professor Winita Hardikar, Head of Liver and Intestinal Transplant program and previous Director of the Department of Gastroenterology and Clinical Nutrition at the Royal Children’s Hospital, Melbourne. She is actively involved in research, with interests in PSC, biliary atresia, PFIC and Alagille’s syndrome. Her early years saw her undertake her post-doctoral studies at Yale University where she studied bile acid transport. We encourage all to join this presentation as sometimes looking at the paediatric presentation can give further glimpses into the adult condition.